Guide: How Is PSSM1 Treated

In this piece, I’m going to discuss the subject “How Is PSSM1 Treated?,” and I’m going to do my best to include as much relevant information as I can.

You can manage PSSM in your horse by providing an

alternate energy source

to sugar Avoid

feeding grains

, sweet feeds and other feedstuffs high in sugar. Fat can be a great alternative. Rice bran or vegetable oils can stabilize blood sugar and provide energy.

What are the symptoms of PSSM in horses?


Symptoms:


clinical signs

of PSSM range from mild to severe. They include sweating, lameness,

sore muscles

, undiagnosed lameness, poor performance, and muscle tremors (“tying up”) These may occur with or without exercise. Under saddle, affected horses may be reluctant to go forward or collect.

Can horses with PSSM eat grass?


Horses:

These low-starch feeds should be fed with

good-quality grass hay

or a maximum of 50 percent alfalfa hay Regular turnout for as much time as possible is critical to successful management of PSSM horses. They do not do well confined to stalls or missing days of exercise.

Can PSSM horses be ridden?


Horses:

Once conditioned, some PSSM horses thrive with four days of exercise as long as they receive daily turnout. For riding horses with type 2 PSSM, a prolonged warm-up with adequate stretching is recommended”.

Horses Fatal: Is PSSM in horses fatal

However, MH has also been found with PSSM and affected horses develop

high body temperature

with signs of tying-up that may be fatal.

Horses Progressive: Is PSSM in horses progressive


polysaccharide storage myopathy

(PSSM) is an inherited

muscle disease

that affects many and diverse breeds of horses. The clinical characteristics of PSSM vary between breeds, from muscle pain, cramping and cell damage with exercise, to progressive muscle atrophy.

What’s the difference between PSSM1 and PSSM2?


Difference:

There are different types of PSSM: PSSM1 and PSSM2. PSSM1 is a

well-defined syndrome

with an established genetic background, and PSSM2 is a generic term for other muscular diseases that also involve the abnormal accumulation of sugar in muscle cells but do not include the genetic defect that causes PSSM1.

Can PSSM cause laminitis?


Laminitis:

Metabolic diseases: Horses with certain metabolic disorders like Cushings, Type II Diabetes (Insulin Resistance), Hypothyroidism or Polysaccharide Storage Myopathy (PSSM) usually develop laminitis from increased production of cortisone and high circulating glucose levels.

Pssm Test Cost: How much does a PSSM test cost

Not all cases of tying up are PSSM related either. Test kits for the five panel test can be obtained by request from the AQHA. For members, the test will cost $85. Nonmembers will pay $125.

What should you feed a horse with PSSM?


Horse:

Forage and feed choices for PSSM horses are centered on minimizing sugar and starch intake. Forage requirements. Forage can be supplied as pasture, hay, or hay alternatives such as pellets or cubes Well-maintained pastures should contain low-sugar grasses and few legumes (clover, alfalfa or lucerne).

Beet Pulp Good: Is beet pulp good for PSSM horses

To the contrary, beet pulp is very low in starch and sugar, usually containing only 2-10% total carbohydrates. Thus, it is a safe feedstuff for horses with metabolic concerns such as equine Cushing’s syndrome,

insulin resistance

and

polysaccharide storage myopathy

(PSSM/EPSM).

Can horses with PSSM have alfalfa?


Alfalfa:

In contrast to what many people believe, alfalfa is actually a good hay for the PSSM horse because its NSC content is typically much lower than most grass hays.

What not to feed a horse that ties up?


Horse:

So for horses prone to tying up use cooked grains like corn, barley and rice in place of oats Tip 5 – Reduce or remove the grains or grain based feeds from the diet on days off. Horses fed their full ration on rest days seem to be more likely to be affected by tying up once they resume work.

Pssm Horses: Is rice bran OK for PSSM horses

Stabilized rice bran is a useful fat source for these horses and provides other nutritional components that can be beneficial. Stabilized rice bran products are often added to the diet at 1-3 lb (0.5-1.4 kg) to boost the fat and caloric value of the diet.

Can you test for PSSM2?


Pssm2:

Researchers at EquiSeq have developed tests for genetic variants that predispose a horse to Polysaccharide Storage Myopathy type 2 (PSSM2) or Myofibrillar Myopathy (MFM), a subtype of PSSM2 These tests identify horses at risk for developing PSSM2/MFM before they show any symptoms.

Can you breed a mare with PSSM?


Mare:

Thus any time a horse with PSSM1 is bred there is a minimum chance of 50% of an affected foal being born even if the selected mate is completely normal The risk of producing an affected offspring when breeding a horse with PSSM1 is much higher because it is a dominant disease.

What is the difference between HYPP and PSSM?


Difference:

Type 1 PSSM is a common cause for tie-up signs in Quarter Horses, Paints, Appaloosas, and warmbloods. PSSM can often be managed with diet and exercise changes but there is no cure or medication used to treat it. HYPP is an inherited

muscle disease

causing an abnormality in how muscle cells manage electrolytes.

Can a horse have PSSM1 and PSSM2?


Pssm1:

Can a horse have both PSSM1 and PSSM2? A10. PSSM1 and PSSM2/MFM are the names of diseases. A horse can have multiple variants (for example, n/P1 n/P2 n/P3 n/P4), but by definition, if this horse has symptoms of exercise intolerance and tests positive for GYS1-R309H (n/P1 or P1/P1), it has PSSM1.

Do Warmbloods get PSSM?


Warmbloods:

About 80% of cases of PSSM diagnosed by biopsy in Warmbloods are PSSM2.

How do you treat PSSM2 in horses?


Horses:

Caring for a horse with PSSM2 Hereditary muscle diseases are not curable. Most PSSM2 affected horses benefit from diets with high protein, and/or supplementation of the amino acids Lysine, Threonine, and Methionine, along with regular exercise Movement is important, so an active or open stall is helpful.

What does 5 panel mean in horses?


Horses:

The Five-Panel Genetic Test These include hyperkalemic periodic paralysis (HYPP), polysaccharide storage myopathy (PSSM), glycogen branching enzyme disease (GBED), hereditary equine regional dermal asthenia (HERDA), and malignant hyperthermia (MH).

How do you take care of a horse in PSSM?


Horse:

The best way to manage PSSM horses is to provide a forage-first low-sugar and starch diet and meet additional energy requirements with dietary fat A consistent exercise routine can also help promote glycogen breakdown in the muscle.

What is the best vitamin E supplement for horses?


Horses:

Most vitamin E supplements consist of alpha-tocopherol because alpha-tocopherol is the most biologically available and well researched isoform of vitamin E. The most efficient way to rapidly increase levels is to administer a natural water-soluble Emcelle Stuart Product supplement (Elevate W.S. or Nano-e).

How do you stop a horse from tying up?


Horse:

Daily exercise is essential, either in the form of turnout, longing, or riding. Sometimes medications such as dantrolene given to fasted horses 90 min before exercise can be helpful in preventing anticipated episodes of tying-up. Another form of tying-up is polysaccharide storage myopathy (PSSM).

Sources


https://extension.umn.edu/horse-health/polysaccharide-storage-myopathy-pssm


https://www.animalgenetics.us/Equine/Genetic_Disease/PSSM.asp


https://ceh.vetmed.ucdavis.edu/health-topics/polysaccharide-storage-myopathy-pssm


https://www.horsejournals.com/horse-care/illness-injury/diseases/understanding-pssm-horses


https://ker.com/equinews/update-pssm-horses/