In summary, treatment of vaginal candidiasis in pregnancy should only be undertaken with guidance from a
healthcare provider
.
topical imidazoles
(miconazole and clotrimazole) have the largest body of evidence regarding safety for both the mother and the fetus during pregnancy.
What antifungals are safe during pregnancy?
For antifungal medications, clotrimazole, miconazole and nystatin are considered first-line agents. Butenafine, ciclopirox, naftifine, oxiconazole and terbinafine may be utilized after the above agents. Econazole should be avoided during the first trimester and used sparingly during 2nd and 3rd trimester.
Is fluconazole safe in pregnancy?
A single dose of fluconazole 150 mg to treat vaginal yeast infection during pregnancy does not appear to be associated with the
birth defects patients
should notify their healthcare professional if they are pregnant or become pregnant while taking fluconazole.
Can I use clotrimazole tablet when pregnant?
Clotrimazole can be used during pregnancy, but only under the supervision of a physician or midwife During pregnancy, the vaginal tablet can be inserted without using an applicator.
Can I use clotrimazole while pregnant?
Clotrimazole is generally considered safe for pregnant women to use If you are using the pessary to treat
vaginal thrush
during pregnancy it is recommended that you insert it with your fingers rather than with the applicator provided. It is very common for pregnant women to suffer from thrush.
Is miconazole safe during pregnancy?
Since topical and vaginal miconazole and clotrimazole are not well absorbed, they are unlikely to be a concern for the pregnancy Most studies have shown that miconazole or clotrimazole at low doses (<400 mg/day) does not increase the chance of birth defects.
Is Flagyl safe in pregnancy?
Pregnancy and breastfeeding Metronidazole is not used in early pregnancy because of potential adverse effects on the fetus Metronidazole is excreted in breast milk. Females who are nursing, because of potential adverse effects on the newborn, should not use metronidazole.
Is
ketoconazole safe
in pregnancy?
There are serious risks of fetal malformations associated with the use of griseofulvin, ketoconazole, voriconazole, flucytosine and potassium iodide. These drugs are contraindicated in pregnancy.
Is ciprofloxacin safe in pregnancy?
According to the Centers for Disease Control and Prevention (CDC), ciprofloxacin (500 mg, orally, two times a day for 60 days) is the antibiotic of choice for initial prophylactic therapy among asymptomatic pregnant women exposed to Bacillus anthracis.
Which is better clotrimazole or miconazole?
In dermatophytosis, miconazole showed accelerated response (75% cleared in 6 weeks) than clotrimazole (56%) In candidiasis, both were found to be effective (80-85%) cure though clotrimazole showed slightly earlier response (40% cure in 6 weeks) against miconazole (30% cure).
What is the safest antibiotic during pregnancy?
- Penicillins, including amoxicillin (Amoxil, Larotid) and ampicillin.
- Cephalosporins, including cefaclor and cephalexin (Keflex)
- Clindamycin (Cleocin, Clinda-Derm, Clindagel)
Is metronidazole 500mg safe during pregnancy?
You can use metronidazole while you’re pregnant.
Can metronidazole be given in pregnancy?
Metronidazole, a nitroimidazole derivative, is a recommended treatment during pregnancy for bacterial vaginosis (BV) and infections with Trichomonas vaginalis (8, 9). Preterm birth has been associated with both BV and T. vaginalis (10, 20).
References
https://pubmed.ncbi.nlm.nih.gov/28449377/
https://www.cdc.gov/std/treatment-guidelines/candidiasis.htm